Vaccines: A major breakthrough. To date, vaccines are rolling out in 25 countries, protecting millions of children. Chemoprevention : Seasonal malaria chemoprevention (SMC) now reaches 54 million children. Perennial malaria chemoprevention (PMC) is also expanding. Improved treatment of children : More febrile children are being diagnosed and treated with effective medicines (ACTs) than in the past. We can end malaria. Not someday, but in our lifetime.